In this study, Ag-doped ZnO powders were synthesized by coprecipitation using zinc sulfate salt and silver nitrate salt as starting materials. For the doping source contained in ZnO target, was used AgNO₃ powder with a various mixing ratio (0, 0.02 and 0.05 wt.%). The obtained materials were investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and specific surface. The antimicrobial property was assessed using Penicillium. The results suggest that Ag-doped ZnO powders exhibits good antimicrobial property and only a very low concentration of silver is needed. This work demonstrates the possible use of these powders as pigments with antimicrobial properties for indoor and outdoor paints.